• (623) 209-7602
  • # 221 Britain Street, Santee, South Carolina 29142, US
  • 0 /10

Comfort Inn & Suites Santee, SC Hotel and Motel


Comfort Inn & Suites Santee SC is a cozy, comfortable and affordable place where you’ll be welcomed heartily. Stay with us at this well-regarded hotel in Santee SC and experience the best for less while taking in the abundant natural of beauty of Orangeburg County. Our hotel is close to Lake Marion, a jewel of central South Carolina. We’re also the first and best place to choose when seeking a place to stay near Lake Marion Golf Course and Lake Marion Bass Fishing as well as Santee Wildlife Refuge, Palmetto Trail and the Santee Welcome Center. Choose us over other hotels in Santee SC and you’ll get plenty of amenities. These include a satisfying free breakfast, free wifi, access to our fitness center and seasonal outdoor pool and more.


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